5 Facts you should know about

Primary biliary cholangitis

Common symptoms are tiredness, itching, and in more advanced cases, jaundice

Abnormalities in liver enzyme tests are usually present and elevated gamma-glutamyl transferase and alkaline phosphatase are found in early disease

Elevations in bilirubin occur in advanced disease

Itching (pruritus) occurs in a majority of severe cases and can develop at any stage of the disease

The prevalence of PBC has risen significantly over the last decade, with an increase of 80% of cases between 2006 and 2014

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