5 Facts you should know about

Cronkhite-Canada syndrome (CCS)

CCS can occur in all ethnic groups

Symptomatic disease onset occurs at a mean age of 59 years

Diarrhea and dysgeusia are the most common initial symptoms

The dermatologic symptoms of alopecia, hyperpigmentation, and onychodystrophy often occurring later in the disease process

Etiology is unknown – but most experts suggest immune dysregulation is the basis of Cronkhite-Canada syndrome

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