5 Facts you should know about

APDS (PASLI syndrome)

Immunodeficiency disease is characterized by increased susceptibility to recurrent and/or severe bacterial and viral infections

The earliest and most frequent manifestations of APDS are infections of the ears, sinuses, and upper and lower respiratory tracts

Small airways disease and bronchiectasis frequently complicate APDS

APDS patients are often afflicted by benign lymphoproliferative disease

Clinical severity ranges from asymptomatic to death in early childhood

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